Steven Beyea, PhD
Assistant Professor of Radiology
Adjunct Prof. of Physics & Biomedical Eng.
Associate Research Officer
Neuroimaging Research Lab
National Research Council Canada
Education
Ph.D. (2000)
Physics
University of New Brunswick
B.Sc. (1995)
1st Class Honours (Physics)
University of New Brunswick
Research and Clinical Interests
Application of Compressed Sensing reconstruction to functional MRI (fMRI)
fMRI and DTI in regions of magnetic susceptibility distortion (e.g. orbital frontal cortex)
Optimization of novel contrast mechanisms for fMRI at 4-T
Improvement of sensitivity/specificity for functional mapping in brain tumour patients
Development of patient-specific multi-modal imaging protocols and analysis techniques
Publications
Past 3 Years
M.T.R. Stevens, R.C.N. D’Arcy, K.N.H. Dillen, G. Stroink, D.B. Clarke & S.D. Beyea "Improved Single-Subject fMRI by ROC-based, Reproducibility Optimized Thresholding" Neuroimage, submitted (2011).
K.D. Brewer, J.A. Rioux, M. Klassen, C.V. Bowen and S.D. Beyea “Signal Displacement in Spiral-In Acquisitions: Simulations & Implications for Imaging in SFG Regions” Magnetic Resonance Imaging, submitted (2011).
D. Holland, C. Liu, E. Mazerolle, X. Song, T. Stevens, C. V. Bowen, A. Sederman, L. Gladden, S. D. Beyea "Does Compressed Sensing Enhance fMRI Sensitivity?" NMR Biomed., submitted (2011).
J.A. Rioux, K.D. Brewer, S.D. Beyea, C.V. Bowen "Quantification of Superparamagnetic Iron Oxide with Large Dynamic Range using turboSPI" J. Magn. Reson., submitted (2011).
J.M. Bray, M. Filiaggi, C.V. Bowen and S.D. Beyea “Degradation & Drug Release in Calcium Polyphosphate Bioceramics: An MRI-Based Characterization”, Acta Biomaterialia, submitted (2011).
J.R. Gawryluk, E. Mazerolle, K.D. Brewer, S.D. Beyea & R.C.N. D’Arcy, “Investigation of fMRI Activation in the Internal Capsule”, BMC Neuro., 12:56 (2011).
Ryan C.N. D’Arcy, Jodie R. Gawryluk, Steven D. Beyea, Sujoy Ghosh Hajra, Kirk W. Feindel, & David B. Clarke "Tracking Cognitive Changes in New-Onset Epilepsy: Functional Imaging Challenges", Epilepsia, 52, 43-46 (2011).
J.R. Gawryluk, R.C.N. D’Arcy, E. Mazerolle, K.D. Brewer & S.D. Beyea “Functional Mapping in the Corpus Collosum: A 4T fMRI Study of White Matter”, Neuroimage, 54, 10-15 (2011).
W. Chen, X. Song, S.D. Beyea, RC.N. D’Arcy, Y. Zhang & K. Rockwood " Advances of Perfusion Magnetic Resonance Imaging in Alzheimer’s Disease" Review Article, Alzheimer's & Dementia, 7 (2), 185-196 (2011).
E.L. Mazerolle, S.D. Beyea, J.R. Gawryluk, K.D. Brewer, C.V. Bowen and R.C.N. D’Arcy “Confirming White Matter fMRI in the Corpus Collosum: Co-Localization with DTI Tractography” Neuroimage 50, 616-621 (2010).
K. Brewer, J. Rioux, R.C.N. D’Arcy, C.V. Bowen & S.D. Beyea “Asymmetric Spin-Echo (ASE) Spiral for Improved BOLD fMRI in Regions of Magnetic Inhomogeneities” NMR in Biomedicine 22 (6), 654-662 (2009).
J.R. Gawryluk, K.D. Brewer, S.D. Beyea & R.C.N. D’Arcy “Optimizing the Detection of White Matter MRI using Asymmetric Spin Echo Spiral” Neuroimage 45, 83-88 (2009).
Presentations
Invited Lectures (Past 3 Years)
J. Rioux, C. Bowen, S.D. Beyea “Techniques for Imaging Novel Therapeutics using SPIO Nanoparticles” Institute for Research in Materials Annual Meeting, Halifax NS (2009).
J.M. Bray, M. Filiaggi, S.D. Beyea “Characterization of Implantable Drug Delivery Bioceramics using Magnetic Resonance Imaging (MRI)”, Biological Materials Symposium - TMS Annual Meeting, San Francisco CA (2009).
S.D. Beyea & R.C.N. D’Arcy “High Field fMRI Sequence Development”, Helsinki University of Technology, Finland, (2008).
K.D. Brewer, S. Patterson, C.V. Bowen & S.D. Beyea “Novel Acquisition Techniques for High Field Functional MRI (fMRI)” Medical Physics Symposium - Canadian Association of Physicists Congress, Quebec City QC (2008).
S.D. Beyea “Developments in MR Neuroimaging at 4T: Novel Applications & Techniques” Medical Physics Seminar Series, Nova Scotia Cancer Centre, Halifax NS (2008).
Conference Presentations (Past Year)
D. Holland, C. Liu, E. Mazerolle, X. Song, T. Stevens, C. V. Bowen, A. Sederman, L. Gladden, S. D. Beyea "Compressed Sensing Reconstruction Improves Variable Density Spiral Functional MRI" 19thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Montreal, Canada (2011).
D. Holland, C. Liu, E. Mazerolle, X. Song, T. Stevens, C. V. Bowen, A. Sederman, L. Gladden, S. D. Beyea " Highly Sparse Spiral fMRI Reconstructed with Compressed Sensing: Trajectory Optimization for BOLD Contrast" 19thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Montreal, Canada (2011).
S. Patterson, C.V. Bowen, S.D. Beyea " FMRI using high flip-angle alternating steady state balanced SSFP supported by Monte Carlo studies" 19thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Montreal, Canada (2011).
J.R. Gawryluk, R.C.N. D’Arcy, S.D. Beyea "White matter fMRI: linking advances in research with neuropsychological measures" 17th Annual Meeting of the Organization of Human Brain Mapping, Quebec City, Canada (2011).
E.L., Mazerolle, K.D. Brewer, S.D. Beyea, J.R. Gawryluk, C.V. Bowen, D.R. DeBay, K.W. Feindel, J.R. Rioux, K. Semba, D. Rasmusson, R.C.N. D’Arcy "Hemodynamic changes in white matter during a breath-hold task do not result from partial volume effects: Implications for white matter fMRI" 17th Annual Meeting of the Organization of Human Brain Mapping, Quebec City, Canada (2011).
X. Song, R.C.N. D’Arcy, J. Fisk, A. Major, S.D. Beyea & K. Rockwood “Correlations of Prefrontal Cortical Activation and Cognitive Performance with Cholinesterase Inhibitor Treatment: A High Field Functional MRI Study” International Conference on Alzheimer’s Disease, Paris, France (2011).
J.A. Rioux, S.D. Beyea & C.V. Bowen “Fast Time-Resolved 3D Single Point Imaging with Compressed Sensing” 18thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Stockholm, Sweden (2010).
K.D. Brewer, J. Rioux, M. Klassen, C.V. Bowen & S.D. Beyea “Recovery of Signal using Spiral-In K-Space Trajectories: Phase Coherence or Intensity Displacement?” 18thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Stockholm, Sweden (2010).
T. Stevens, S.D. Beyea, R.C.N. D’Arcy, D. Clarke & C.V. Bowen “Development of an Automated Threshold Technique based on Reproducibility of fMRI Activation” 18thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Stockholm, Sweden (2010).
K.D. Brewer, J.R. Rioux, R.C.N. D’Arcy, C.V. Bowen & S.D. Beyea “Understanding the Limitations of the Effectiveness of Z-Shim for use with fMRI” 18thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Stockholm, Sweden (2010).
K.D. Brewer, L. Cherpak, T. Stevens, R.C.N. D’Arcy, C.V. Bowen & S.D. Beyea “Increasing fMRI Specificity using Asymmetric Spin Echo (ASE) Spiral: An ROC-based Analysis” 18thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Stockholm, Sweden (2010).
L. Cherpak, K.D. Brewer, J. Dube, J. Gawryluk, N. Pelot, C.V. Bowen, R.C.N. D’Arcy, S.D. Beyea “Multi-Sequence Comparison of Temporal Lobe fMRI Activation at 4-T” 18thScientific Meeting of the International Society for Magnetic Resonance in Medicine, Stockholm, Sweden (2010).
R.C.N. D'Arcy, J, Gawryluk, X. Song, E. Mazerolle, S. Beyea & D. Clarke "White Matter fMRI in a Collosotomy Patient" 16th Annual Meeting of the Organization of Human Brain Mapping, Barcelona, Spain (2010).
X. Song, R.C.N. D’Arcy, J. Fisk, A. Major, S.D. Beyea & K. Rockwood “Encoding Reinforcement Improves Memory in Older Adults – Evidence from a High-Field Functional MRI Study” International Conference on Alzheimer’s Disease, Honolulu, Hawaii (2010).
Grants & Awards
Grants (Currently Held)
Natural Sciences and Engineering Research Council –
Discovery Grant
Title: MRI Characterization of Implantable Drug Delivery Bioceramics
2007-2012, $85,000, Principal Investigator
Canadian Institutes for Health Research - Operating Grant
Title: Quantitative Proton Spectroscopy of White Matter at 4 Tesla in First Episode Psychosis Part II: A Clinical Study
2010-2013, $226,620, Co-Investigator
Canadian Institutes for Health Research - China-Canada Joint Health Research Initiative
Title: Functional Neuroimaging of White Matter Integrity in Cognitive Dysfunction: Linking Neuroscience Research with Clinical Evaluation
2010-2013, $149,400, Co-Investigator
Dalhousie Psychiatry Research Fund
Title: NPAS3 variants in schizophrenia: a neuroimaging study
2011-2012, $9,930, Co-Investigator
Awards (Past 2 Years)
Canadian Public Service Award of Excellence (2011)
Team award to the Neurotouch Surgical Oncology Team
National Research Council Outstanding Achievement Award (2010)
Citation: "For the regional initiatives in the translation of non-invasive technologies to clinical neurosciences and to their commercialization"
Sites of Interest
National Research Council Canada: Institute for Biodiagnostics |
HALIFAX, NOVA SCOTIA | CANADA
